Molecular and Genetic Investigation of Tau in Chronic Traumatic Encephalopthy

Abstract

Repetitive mild TBI leads to chronic traumatic encephalopathy (CTE), but the underlying molecular changes remain unclear. Here, biochemical and genetic studies that deepen our understanding of the pathogenesis of CTE will be performed, facilitating diagnosis and therapeutic development.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2016
Accession Number
AD1033161

Entities

People

  • John F. Crary

Organizations

  • Icahn School of Medicine at Mount Sinai

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Alzheimer Disease
  • Biomedical Research
  • Blood
  • Blood Vessels
  • Brain Injuries
  • Cellular Structures
  • Chronic Encephalopathy
  • Cognitive Impairment
  • Diseases And Disorders
  • Frequency
  • Genetics
  • Materials
  • Medical Personnel
  • Neurodegenerative Diseases
  • Neurons
  • Professional Development

Fields of Study

  • Medicine
  • Psychology

Readers

  • Traumatic Brain Injury (TBI) and Cognitive Aging in the Guam and Border Populations Affected by Alzheimer's Disease and Tau-Associated Dementias.

Technology Areas

  • Biotechnology