Bioengineered Hydrogel to Inhibit Post-Traumatic Central Nervous System Scarring

Abstract

We have successfully synthesized and characterized an injectable hydrogel biomaterial with tunable thermosensitivity and the capability for covalent attachment of therapeutic peptides. This new material can be tuned and tested with the purpose of delivery a gel to the injured brain that becomes responsive to the injury environment. This work resulted in a publication in the Journal of Controlled Release (J Control Release. 2015 Jun 28;208:76-84).

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2016
Accession Number
AD1033191

Entities

People

  • Philip J. Horner
  • Suzie H. Pun

Organizations

  • University of Washington

Tags

DTIC Thesaurus Topics

  • Biomaterials
  • Cells
  • Central Nervous System
  • Gels
  • Hydrogels
  • Liquid Chromatography
  • Materials
  • Nervous System
  • Polymers
  • Spinal Cord
  • Spinal Injuries
  • Stem Cells
  • Transplants

Readers

  • Nanocomposite Materials Science
  • Neurotrauma and Rehabilitation Medicine.
  • Technical Research and Report Writing.

Technology Areas

  • Biotechnology