EMERGE: Engineered Materials that Create Environments for ReGeneration via Electric Field

Abstract

The report herein describes progress made in the first year of EMERGE: Engineered Materials the Create Environments for ReGeneration via Electric Fields. The objective of the project is to develop a next-generation ocular implant material with biomimetic chemistry and nanotopography with unique drug delivery functionality to 1) provide appropriate biochemical and biophysical cues for enhanced cell migration, differentiation and proliferation and 2) deliver wound electric field enhancing pharmaceuticals for enhanced bioelectronics cues. To this end, we are developing a collagen material with tailored nano topography with ability to deliver endogenous wound electric field-enhancing molecules that will encourage and accelerate the wound healing process. We monitor wound electrophysiology as a function of time using a vibrating probe.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2016
Accession Number
AD1033539

Entities

People

  • Brian Reid
  • Lance Baird
  • Leslie Hamilton
  • Min Zhao
  • Morgana Trexler
  • Xiomara Caderon-colon

Organizations

  • Johns Hopkins University

Tags

DTIC Thesaurus Topics

  • Brain Injuries
  • Cell Movement
  • Cells
  • Chemistry
  • Composite Materials
  • Electric Fields
  • Engineered Materials
  • Eye Injuries
  • Health Services
  • Materials
  • Materials Laboratories
  • Materials Processing
  • Materials Science
  • Mechanical Properties
  • Medical Personnel
  • Military Hospitals
  • Wound Healing

Readers

  • Nanoscale Plasmonic Nanotechnology
  • Trauma Surgery or Emergency Medicine.

Technology Areas

  • Biotechnology