Super-Resolution Microscopy by Microspheres Embedded in Movable Slabs
Abstract
Recent years have witnessed a breakthrough in achieving truly nanoscale resolution by a fluorescent super-resolution microscopy. The label-free microscopy develops more slowly than fluorescent microscopy for two reasons. First, the mechanisms of label-free imaging rely on much more subtle light-scattering processes in nanoplasmonic or biomedical objects that result in lower effective contrast of images. Second, good point-sources in a form of dye-molecules, fluorophores or quantum dots are not readily available in a label-free microscopy that complicates the experimental quantification of resolution.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 03, 2015
- Accession Number
- AD1034618
Entities
People
- Augustine M. Urbas
- Dennis Jr E. Walker
- Kenneth W. Allen
- Nicholaos I. Limberopoulos
- Vasily N. Astratov
- Vladimir Liberman
- Yangcheng Li
Organizations
- MIT Lincoln Laboratory