Beta Blockers for the Prevention of Acute Exacerbations of COPD

Abstract

We are conducting a randomized, placebo-controlled trial to definitively assess the impact of metoprolol succinate on the rate of COPD exacerbations. This is a multicenter, placebo-controlled, double-blind, prospective randomized trial that will enroll 1028 patients with at least moderately severe COPD over a 3-year period. Major activities for this reporting period have centered on contracting, regulatory approvals, training, site initiation and enrollment at clinical sites. Upon execution of contracts and IRB approvals enrollment has been steadily increasing. The monthly enrollment goal is 28.5 across all sites, with each site enrolling an average of 2-3 participants per month. Several sites have met and exceeded this goal in August and September and we expect this trend to continue.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2016
Accession Number
AD1034632

Entities

People

  • Mark T Dransfield

Organizations

  • University of Alabama at Birmingham

Tags

DTIC Thesaurus Topics

  • Cardiac Arrhythmias
  • Cardiovascular Diagnostic Techniques
  • Cardiovascular Diseases
  • Cardiovascular Physiological Phenomena
  • Cardiovascular System
  • Health Services
  • Heart Rate
  • Lung Diseases
  • Medical Personnel
  • Myocardial Ischemia
  • Patient Care
  • Side Effects
  • Therapy

Fields of Study

  • Medicine

Readers

  • Clinical Trial Research.
  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.