Cross-Discipline Bio-Nanostructured Enhanced Photonic Multimode-Sensor Science

Abstract

This cross-discipline experimental study aimed to combine soft material science with nanotechnology and multi-physics modeling to produce adaptable bio-nanostructure based on Quantum Dots and Proteins, dropping therefore the cytotoxicity and open new applications in biomedicine, among other areas. We observe from MALDI-TOF analysis two type of proteins in the coating of the Quantum Dots synthetized in bacterias: proteins that interact with nucleotides or DNA and chaperone proteins. All these sequences recollected were annotated and analyzed using bioinformatics tools. At the same time, some of the proteins with structural information were model and characterized the residues accessible to the solvent, in order to evaluate a molecular mechanism of the condensation process of the proteins on the surface of the Quantum Dots.

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Document Details

Document Type
Technical Report
Publication Date
May 23, 2017
Accession Number
AD1036353

Entities

People

  • Fernando D Gonzalez-nilo

Tags

Communities of Interest

  • Advanced Electronics

DTIC Thesaurus Topics

  • Air Force Research Laboratories
  • Amino Acids
  • Bacteria
  • Chemical Synthesis
  • Chemistry
  • Computational Chemistry
  • Crystal Structure
  • Gammaproteobacteria
  • Keto Acids
  • Metallic Nanoparticles
  • Molecular Dynamics
  • Nanoparticles
  • Nanotechnology
  • Nucleotides
  • Proteins
  • Quantum Dots
  • Spectra

Readers

  • Molecular and Cellular Biochemistry
  • Nanocomposite Materials Science
  • Quantum Dot Semiconductor Device Photonics and Graphene Optoelectronic Materials and THz Physics.

Technology Areas

  • Biotechnology
  • Microelectronics
  • Quantum Computing