Porcine Collagen Matrix With And Without Enamel Matrix Derivative For The Treatment Of Gingival Recession Defects

Abstract

The purpose of this study is to compare the effectiveness of a porcine collagen matrix (CM), with or without the addition of enamel matrix derivative (EMD) in the treatment of Miller Class I, II or III recession defects. This will be a prospective, single-blinded, randomized, split-mouth study. One defect will receive CM+EMD (test), while the other will receive CM (control) alone. MethodsThe treatment of 30 similarly sized Miller class I, II or III recession defects on single-rooted teeth using coronally advanced flaps with CM + EMD or CM alone will be evaluated. The subjects will be in good health, non-smokers, periodontally healthy except for recession, have good oral hygiene and have no contraindications to periodontal surgery. Subjects will have matching recession defects that measure within 1 mm of each other on single-rooted teeth. One defect will be randomly assigned as the test group receiving CM + EMD, and the other as the control group receiving only CM. Measurements will be made using a UNC-15 periodontal probe, custom acrylic stent and digital calipers and will include: probing depth (PD), clinical attachment level (CAL), vertical recession (RD) and width of keratinized tissue (KTW). The measurements will be taken at baseline (on the day of surgery), and at 3 and 6 months post-surgery.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2016
Accession Number
AD1036435

Entities

People

  • Christopher T. Barth

Organizations

  • Uniformed Services University of the Health Sciences

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Anatomy
  • Attachment
  • Biological Factors
  • Collagen
  • Connective Tissue
  • Data Analysis
  • Materials
  • Measurement
  • Mouth Diseases
  • Oral Hygiene
  • Pain
  • Periodontics
  • Surgery
  • Teeth
  • Therapy
  • Tissues
  • Transplants

Fields of Study

  • Medicine

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