Salivary Proteomic and MicroRNA Biomarkers Development for Lung Cancer Detection

Abstract

This is a lung cancer biomarker development project to test the hypothesis that there are discriminatory biomarkers in saliva that can detect lung cancer with the aim to reduce the number unnecessary diagnostic workups (bronchoscopy) in patients with suspicious chest symptoms. The major goal is to perform a properly powered biomarker discovery and validation of salivary miRNA and proteomic biomarkers for detection of lung cancer based on PRoBE design principles (prospective-specimen-collection and retrospective-blinded-evaluation). The outcome of this project will be a panel of validated non-invasive saliva-based biomarkers for detection of lung cancer.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2016
Accession Number
AD1036999

Entities

People

  • David T. Wong

Organizations

  • University of California

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Blood
  • Body Fluids
  • Cancer
  • Cells
  • Cellular Structures
  • Chemistry
  • Data Analysis
  • Data Mining
  • Data Sets
  • Detection
  • Diseases And Disorders
  • Environment
  • Health Services
  • Information Science
  • Neoplasms
  • Stem Cells

Readers

  • Oncology and Biomarker-Based Cancer Detection.

Technology Areas

  • Biotechnology