Light-based Modeling and Control of Circadian Rhythm

Abstract

The full scope of this research is to develop a robust and reliable circadian phase estimation system, and use it for model identification and light-based control design. The objective of this project is to develop preliminary results in the following directions to lay the foundation of the full research. 1. Circadian phase estimation and control: Demonstrate the applicability of the adaptive notch filter (ANF) to extract circadian phase from noisy Drosophila locomotive activity measurements and the efficacy of using the ANF output for light based circadian phase control. 2. Pathway to human deployment: Demonstrate the feasibility of a human wearable sensor that could be used with the ANF algorithm to extract the circadian phase of human users.

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Document Details

Document Type
Technical Report
Publication Date
Aug 29, 2016
Accession Number
AD1037334

Entities

People

  • Agung Julius
  • John T. Wen

Organizations

  • Rensselaer Polytechnic Institute

Tags

Communities of Interest

  • Biomedical
  • Materials and Manufacturing Processes
  • Sensors

DTIC Thesaurus Topics

  • Abstracts
  • Agreements
  • Algorithms
  • Circadian Rhythms
  • Control Systems
  • Department Of Defense
  • Deployment
  • Drosophila
  • Engineering
  • Entrainment
  • Feedback
  • Filters
  • Mathematics
  • Notch Filters
  • Phase Control
  • Signal Processing
  • Students

Readers

  • Neuroscience
  • Oncology
  • Robotics and Automation.