Center for Engineered Biomedical Devices

Abstract

BACKGROUND: Intervertebral disc (IVD) degeneration is a major source of lower back pain. Current treatment strategies aim to alleviate the associated symptoms and not on restoring the biological function of the intervertebral disc. PURPOSE: The objective of this study is to construct an injectable scaffold in vitro as a therapeutic delivery system to improve the mechanical properties of the nucleus pulposus (NP) of IVD to withstand physiologic loading.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 2013
Accession Number
AD1039219

Entities

People

  • Daniel S. Engebretson

Organizations

  • University of South Dakota

Tags

DTIC Thesaurus Topics

  • Alginic Acid
  • Azo Compounds
  • Biomedical Engineering
  • Calcium Compounds
  • Cartilage
  • Cells
  • Confocal Microscopy
  • Culture Techniques
  • Engineering
  • Mechanical Properties
  • Modulus Of Elasticity
  • Pain
  • Polysaccharides
  • South Dakota
  • Statistical Analysis
  • Three Dimensional
  • Tissue Engineering

Fields of Study

  • Medicine

Readers

  • Molecular and Cellular Biochemistry
  • Neurotrauma and Rehabilitation Medicine.

Technology Areas

  • Biotechnology