Auer Rod Formation in Mature Eosinophils is an Extremely Rare Manifestation of Myelodysplasia
Abstract
A 50-year-old woman was discovered to have incidental mild leukocytopenia and thrombocytopenia. Rare blasts and dysplastic neutrophils were seen on peripheral blood smear. A bone marrow examination revealed dysplastic granulocytes and megakaryocytes with 1% blasts. Cytogenetic testing demonstrated a complex karyotype including del(5q). A diagnosis of refractory cytopenia with multilineage dysplasia was rendered (2008 WHO). Her bone marrow blast count subsequently increased to 10% and she underwent an allogeneic peripheral blood stem cell transplant. She was doing well; however, one year post-transplant, a bone marrow biopsy again showed 10% blasts and dysplastic myeloid cells, including rare dysplastic eosinophils with Auer rod-like bodies, consistent with recurrent high grade myeloid malignancy.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 08, 2017
- Accession Number
- AD1040216
Entities
People
- Jordan M. Hall
- Sierra Musick
Organizations
- 59th Medical Wing