Monitoring of Creatine Kinase Levels in Specific Military Populations for Early Treatment

Abstract

The high physical demand of military environments such as basic training, selection schools, and advanced courses subject the member to extreme muscle usage with potentially inadequate recovery time. As the muscle breaks down with extreme use, the protein, myoglobin, builds up in the blood. If the individual does not have sufficient rest time, allowing the body to recover, health problems can arise as the kidneys attempt to process the excess myoglobin. A blockage in the kidneys due to the protein can occur resulting in decreased function culminating in kidney failure and death if untreated. Extreme skeletal muscle breakdown that can result in kidney issues is rhabdomyolysis. Creatine kinase (CK) is an enzyme released by damaged muscle and is an accurate marker for muscle injury. Without CK monitoring, extreme muscle stiffness could be considered normal due to recent increase in physical activity. Determining a subset of military members that are at higher risk for extreme muscle damage can create a small population that would benefit the most from CK monitoring. Preexisting health conditions can increase an individuals susceptibility to rhabdomyolysis. The military allows a few of these preexisting health conditions upon entry while others are allowed after a member is on active duty. Monitoring this subset population during extreme exercise for CK levels can alert when proactive preventative action could prevent permanent damage.

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Document Details

Document Type
Technical Report
Publication Date
Feb 01, 2016
Accession Number
AD1041086

Entities

People

  • Lindsey L. Mahoney

Organizations

  • Air Command and Staff College

Tags

DTIC Thesaurus Topics

  • Basic Training
  • Blood
  • Health Services
  • Medical Personnel
  • Military Training
  • Muscular Diseases
  • Skeletal Muscle
  • Therapy

Fields of Study

  • Medicine

Readers

  • Educational Psychology
  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Molecular and Cellular Biochemistry