Homeostatic and Circadian Abnormalities in Sleep and Arousal in Gulf War Syndrome

Abstract

The purpose of this study is to assess sleep and wake parameters in veterans of the first Gulf War who have fatigue and other symptoms compared with veterans who do not have fatigue utilizing novel assessment techniques including high density EEG and temperature. This research study is in the data collection and data processing phase. The most significant findings to date in this study during the research period include continued evidence of high density EEG marked broad band reduction in neural activity circumscribed in the frontal cortex in NREM sleep. Slow wave sleep is considered to play a role in the recovery and restorative aspects of sleep, and is one bandwidth affected. In addition, melatonin curves, particularly dim light melatonin onset, which is well-tied with circadian sleep/wake and subsequent feelings of fatigue/alertness show different projections in veterans endorsing fatigue than those who do not.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2016
Accession Number
AD1041420

Entities

People

  • Giulio Tononi
  • Ruth Benca
  • Timothy M. Juergens

Organizations

  • University of Wisconsin–Madison

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biomedical Research
  • Body Temperature
  • Brain
  • Brain Waves
  • Circadian Rhythms
  • Cognitive Impairment
  • Data Analysis
  • Data Processing
  • Diseases And Disorders
  • Dyssomnias
  • Frequency
  • Melatonin
  • Persian Gulf Syndrome
  • Power Spectra
  • Sleep Deprivation
  • Sleep Disorders
  • Structural Integrity

Fields of Study

  • Psychology

Readers

  • Circadian Sleep-Wake Regulation and Chronobiology
  • Electronics Engineering
  • Neurotrauma and Rehabilitation Medicine.