Safety Parameter Considerations of Anodal Transcranial Direct Current Stimulation in Rats

Abstract

A commonly referenced transcranial Direct Current Stimulation (tDCS) safety threshold derives from tDCS lesion studies in the rat and relies on electrode current density (and related electrode charge density) to support clinical guidelines. Concerns about the role of polarity (e.g., anodal tDCS), sub-lesion threshold injury (e.g., neuroinflammatory processes), and role of electrode montage across rodent and human studies support further investigation into animal models of tDCS safety.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2017
Accession Number
AD1041628

Entities

People

  • Dennis Truong
  • Jessica A. Wagner
  • Mark P. Jackson
  • Marom Bikson
  • Milene L. Brownlow
  • R. A. Mckinley
  • Ryan Jankord

Organizations

  • Infoscitex Corporation

Tags

Communities of Interest

  • Human Systems

DTIC Thesaurus Topics

  • Air Force
  • Air Force Research Laboratories
  • Biological Staining And Labeling
  • Brain
  • Brain Injuries
  • Cells
  • Charge Density
  • Chemistry
  • Computational Modeling
  • Current Density
  • Depression
  • Direct Current
  • Electrodes
  • Neuroglia
  • Neurosciences
  • Polarity
  • Statistical Analysis

Fields of Study

  • Psychology

Readers

  • Aviation Safety Risk Assessment.
  • Electrochemical Surface Science
  • Theoretical Analysis.