Follistatin: A Potential Anabolic Treatment for Re-Innervated Muscle

Abstract

Follistatin is a possible anabolic treatment for denervation atrophy induced muscle weakness following prolonged denervation. Adenovirus delivery of Recombinant FS-288 DNA isoform does not induce hypertrophy in normal rodent gastrocnemius muscle. The efficacy of Adenoassociated virus delivery of FS-288 DNA or direct delivery of recombinant FS-288 protein is currently not known.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2017
Accession Number
AD1044365

Entities

People

  • Jonathan Isaacs

Organizations

  • Virginia Commonwealth University

Tags

DTIC Thesaurus Topics

  • Cells
  • Data Analysis
  • Descriptive Analytics
  • Drug Therapy
  • Information Science
  • Medical Personnel
  • Muscle Fibers
  • Neuromuscular Diseases
  • Peripheral Nervous System
  • Pilot Studies
  • Recombinant Dna
  • Standards
  • Statistical Analysis
  • Students
  • Surgery
  • Virotherapy
  • Viruses

Fields of Study

  • Biology
  • Medicine

Readers

  • Exercise and Sports Science.
  • Molecular Genetics
  • Oncology (Cancer Research).