Investigate the Role of Obesity in Ovarian Cancer Initiation and Progression

Abstract

During this funding period we focused on generating the mouse models that will enable achieve the goals of the proposed research. The aim of this project is to identify genes and pathways in ovarian stem cells and in transformed ovarian cells affected by obesity that lead to ovarian cancer initiation and progression.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2017
Accession Number
AD1044797

Entities

People

  • Angeliki Chalkiadaki
  • Leonard P. Guarente

Organizations

  • Massachusetts Institute of Technology

Tags

DTIC Thesaurus Topics

  • Adipose Tissue
  • Anatomy
  • Biological Sciences
  • Biomedical Research
  • Cancer
  • Cells
  • Epithelial Cells
  • Gene Expression
  • Genes
  • Medical Personnel
  • Neoplasms
  • Ovarian Cancer
  • Professional Development
  • Stem Cells
  • Technology Transfer
  • Therapy
  • Tissues

Readers

  • Molecular and genetic basis of cancer.
  • Oncology (Cancer Research).

Technology Areas

  • Biotechnology