Automated Comprehensive Evaluation of mTBI Visual Dysfunction

Abstract

The purpose of this study is to validate the Neuro-Ophthalmic Device (NODe) test battery that provides the highest sensitivity and specificity for the detection of oculomotor and high order visual processing dysfunctions on a large population of Warfighters with acute mTBI as compared to healthy age-matched controls. This study also will demonstrate that a comprehensive combination of biomarkers will be more specific to mTBI than any one test alone and that the tests within the NODe test battery can serve as objective biomarkers for acute mTBI. Two hundred acute mTBI (72 hrs post injury) and 200 age-matched non-TBI (controls) military personnel will be recruited from the patient population at Womack Army Medical Center (WAMC). The central hypothesis is that a NODe test panel evaluating visual function can detect neurological and ophthalmological changes induced by acute mTBI compared to age-matched controls.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 2017
Accession Number
AD1045155

Entities

People

  • José E. Capó-aponte

Organizations

  • Womack Army Medical Center

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biological Markers
  • Brain Injuries
  • Computer Vision
  • Data Analysis
  • Data Sets
  • Department Of Defense
  • Detection
  • Dysfunction
  • Information Science
  • Institutional Review Board
  • Medical Personnel
  • Military Personnel
  • Sensitivity
  • Standards
  • Statistical Analysis
  • Test And Evaluation
  • Traumatic Stress Disorder

Readers

  • Aerospace Test and Evaluation
  • Neurotrauma and Rehabilitation Medicine.