Omega-3 Polyunsaturated Fatty Acid Status, Microglial Activation, Stress Resilience, and Cognitive Performance

Abstract

Background: Recent studies in healthy civilian and military populations indicate a strong relationship between red blood cell (RBC) n-3 polyunsaturated fatty acids (PUFA) levels and cognitive performance, mood, impulsivity and suicide. However, the precise brain mechanisms that underlie these behavioral impairments in n-3 PUFA deficient individuals are largely unknown. Here we seek to elucidate the underlying immunological mechanisms by which n-3 PUFA exerts its benefits on brain and behavior.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2017
Accession Number
AD1045687

Entities

People

  • Rajesh Narendran

Organizations

  • University of Pittsburgh

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biomedical Research
  • Blood
  • Blood Cells
  • Blood Flow
  • Brain Injuries
  • Cells
  • Data Analysis
  • Fatty Acids
  • Genetics
  • Genotypes
  • Medical Genetics
  • Medical Personnel
  • Patent Applications
  • Positron Emission Tomography
  • Positron Emissions
  • Resilience
  • Standards

Fields of Study

  • Biology

Readers

  • Immunology and Pathology
  • Military Logistics and Supply Chain Management
  • Psychological Intervention/Treatment for Stress, Anxiety, PTSD, and Related Emotional and Cognitive Health Symptoms.