Mechanisms Underlying Stress Fracture and the Influence of Sex and Race/Ethnicity

Abstract

This cross-sectional clinical study aims to examine potential mechanisms contributing to stress fracture risk. In particular, in Study 1, we will perform advanced skeletal imaging along with gait-assessments in subjects with history of a single vs multiple vs no prior stress fractures. In addition, in Aim 2, we will perform advanced imaging to delineate variation in skeletal features according to sex and race/ethnic-origin that may contribute or protect from stress fracture. To date, we have enrolled 21 subjects in Study 1 with an additional 9 subjects scheduled for their visit. Enrollment for both Aims is ongoing. Skeletal assessments are behind schedule due to the delay in installation of the second generation high-resolution peripheral quantitative computed tomography device at MGH. As studies are ongoing, we have not performed any data analyses.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2017
Accession Number
AD1046205

Entities

People

  • Kristin Popp
  • Mary L. Bouxsein
  • Sara Rudolph
  • Signe Caksa

Organizations

  • Massachusetts General Hospital

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biomechanics
  • Biomedical Research
  • Bone Fractures
  • Data Analysis
  • Data Science
  • Demographic Cohorts
  • Department Of Defense
  • Electronic Mail
  • Finite Element Analysis
  • Health Services
  • High Resolution
  • Institutional Review Board
  • Lower Extremity
  • Medical Personnel
  • Statistical Analysis
  • Tomography
  • X-Ray Computed Tomography

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