A Novel Immune-Intact Mouse Model of Prostate Cancer Bone Metastasis: Mechanisms of Chemotaxis and Bone Colonization

Abstract

The proposed studies will help dissect the interplay between CXCL12/ CXCR4 and RANKL/ RANK pathways in prostate cancer bone metastasis in the context of a host with an intact immune system.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2017
Accession Number
AD1046241

Entities

People

  • Srinivas Nandana

Organizations

  • Cedars-Sinai Medical Center

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Bone Marrow
  • Bone Marrow Cells
  • Cancer
  • Cell Line
  • Cell Physiological Processes
  • Cells
  • Gene Expression
  • Imaging Techniques
  • Immune System
  • Lymphocytes
  • Metastasis
  • Myeloid Cells
  • Neoplasms
  • Prostate
  • Prostate Cancer
  • X Rays

Fields of Study

  • Biology
  • Mathematics

Readers

  • Oncology (Cancer Research).