Guided Interventions for Prostate Cancer Using 3D-Transurethral Ultrasound and MRI Fusion

Abstract

Gland-sparing procedures that target specific areas of the prostate have been reported, using laser and HIFU techniques. These focal therapies require real-timevisualization of the prostate during intervention, which is cumbersome to perform while the patient is in an MRI. Magnetic Resonance-Ultrasound (MR-US) fusion allows for specific targeting of the tumors in real-time during clinical interventions, outside of an MR suite. However, existing MR-US fusion exclusively utilizes TRUS. By utilizing a circumferentially wrapped catheter-based transducer, the entire prostate may be visualized at once; improving image registration and reducing motion errors. 3D TUUS imaging has been demonstrated in a phantom setting illustrating that the entire prostate gland can be visualized at once. This imaging advance may serve as a platform technology allowing the development of image guided focal prostate therapy.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2017
Accession Number
AD1046580

Entities

People

  • George Saddik

Organizations

  • University of California

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Catheters
  • Health Services
  • Image Registration
  • Institutional Review Board
  • Intervention
  • Magnetic Resonance
  • Medical Personnel
  • Neoplasms
  • Pilot Studies
  • Prostate
  • Prostate Cancer
  • Prostheses And Implants
  • Standards
  • Therapy
  • Training
  • Ultrasounds

Fields of Study

  • Medicine
  • Physics

Readers

  • Medical Imaging.

Technology Areas

  • Directed Energy