An in Vivo Investigation of Brain Inflammation in Gulf War Illness with Integrated PET/MR Imaging

Abstract

This project is aimed at evaluating the contribution of brain glia to the pathophysiology of Gulf War Illness, as well as fibromyalgia (a functional pain disorder characterized by similar symptoms). So far we have completed administrative and regulatory review, have begun subject enrollment, and completed some preliminary analyses. Over 200 participants have been prescreened for the study. Of those, eighteen participants have completed the study, while an additional twelve participants were enrolled and found to be ineligible at the time of screening. Throughout the recruitment process, we have actively modified our inclusion criteria to address concerns of ambiguity as they have arisen. Recruitment was slower than anticipated initially, but has rapidly picked up over the past few months.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2016
Accession Number
AD1047202

Entities

People

  • Marco L Loggia

Organizations

  • Massachusetts General Hospital

Tags

DTIC Thesaurus Topics

  • Brain
  • Data Analysis
  • Department Of Defense
  • Diagnostic Imaging
  • Diseases And Disorders
  • Health Services
  • Inflammation
  • Magnetic Resonance
  • Magnetic Resonance Imaging
  • Medical Personnel
  • Nervous System
  • Neuroglia
  • Neuropathy
  • Pain
  • Pathophysiology
  • Persian Gulf Syndrome
  • Pilot Studies

Readers

  • Clinical Trial Research.
  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.