Evaluation of the Physiological Challenges in Extreme Environments: Implications for Enhanced Training, Operational Performance and Sex-Specific Responses

Abstract

The specific aim of the second segment of this project series was to determine the impacts of environmental conditions on specific markers of exercise training response and/or acclimation. Untrained males (n=36) served as study participants and were stratified across three training environments 1) control (~20C, 30% RH), 2) heat (~33C, 30% RH), or 3) cold (~7C, 30% RH) environments. Daily training was prescribed for a period of 14 days. Following a controlled diet and exercise plan the day before and after overnight fast participants reported to the laboratory in the early morning hours. A muscle biopsy was obtained from the vastus lateralis (randomized, counter-balanced leg) before starting exercise (Pre) (days 1 and 15). Participants then exercised for 60 minutes at 60% of maximal aerobic capacity in one of the above-described environments. At the conclusion of the exercise trial, participants recovered (seated rest, under normal laboratory conditions) for four hours before a final muscle biopsy was taken (days 1 and 15). The additional four hours was necessary for the genes of interest to peak following exercise as previously described. Data was analyzed using a mixed design ANOVA with repeated measures between the training groups and across time, two-way 2 x 3 ANOVA (time x trial). A probability of type I error of less than 5 % was considered significant (p < 0.05). At the time of this report, only a portion of the data has been analyzed. However, we have completed all study participant training and testing for this phase of the study (males).

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2017
Accession Number
AD1047896

Entities

People

  • Brent C. Ruby
  • Dustin Slivka

Organizations

  • University of Montana

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acclimatization
  • Barometric Pressure
  • Biological Sciences
  • Biomedical Research
  • Blood
  • Chemistry
  • Department Of Defense
  • Environment
  • Extreme Environments
  • Gene Expression
  • Heart
  • High Altitude
  • Institutional Review Board
  • Oxygenation
  • Physiology
  • Proteins
  • Training

Readers

  • Exercise and Sports Science.
  • Regression Analysis.