Supplemental Perioperative Oxygen to Reduce Surgical Site Infection after High Energy Fracture Surgery

Abstract

Our study is a multi-center prospective randomized treatment trial investigating if supplemental perioperative oxygen use will reduce surgical site infection after surgery on fractures with a high risk of infection. The study utilizes the DOD-funded Major Extremity Research Consortium (METRC). The study population is calcaneus, pilon, and tibial plateau fractures. During the first year we created a protocol committee, designed and approved the protocol and CRFs, obtained IRB approval. We have enrolled 1000 patients at 20 centers. Follow up rate has been strong with 91 at 12 months. Based on feedback from the DSMB we have increased our enrollment goal to 1200 and anticipate achieving this in the next 6 months.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2017
Accession Number
AD1047991

Entities

People

  • Robert V. O'toole

Organizations

  • University of Maryland, Baltimore

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Consortiums
  • Costs
  • Department Of Defense
  • Diseases And Disorders
  • Energy
  • Feedback
  • Foot Bones
  • High Energy
  • Infection
  • Lower Extremity
  • Maryland
  • Medical Personnel
  • Physicians
  • Predictive Modeling
  • Public Health
  • Wound Infections

Fields of Study

  • Medicine

Readers

  • Clinical Trial Research.
  • Neurotrauma and Rehabilitation Medicine.