A Novel Approach Using Volumetric Dynamic Airway CT to Determine Optimal Positive End Expiratory Pressure (PEEP) Settings in Neonates Requiring Long-Term Ventilator Support

Abstract

Positive End Expiratory Pressure (PEEP) is a key mechanical ventilator setting in neonates with bronchopulmonary dysplasia (BPD). Excessive PEEP may result in insufficient CO2 elimination and lung damage, while insufficient PEEP can result in impaired gas exchange secondary to airway and alveolar collapse. Determining PEEP settings based on clinical parameters alone is suboptimal due to the inability to titrate pressure with airway dimensions. The purpose of this study is to describe our experience using dynamic airway CT to determine the lowest PEEP setting sufficient to maintain airway patency in BPD patients requiring long-term ventilator support.

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Document Details

Document Type
Technical Report
Publication Date
May 15, 2018
Accession Number
AD1048098

Entities

People

  • Lauren A. May
  • Pamela Ketwaroo
  • Prakash M. Masand
  • R. P. Guillerman
  • Rajesh Krishnamurthy
  • Siddharth P. Jadhav

Organizations

  • 59th Medical Wing

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Air Force
  • Department Of Defense
  • Directives
  • Dysplasia
  • Governments
  • Health Services
  • Hospitals
  • Hypertension
  • Instructions
  • Pulmonary Hypertension
  • Radiology
  • United States
  • Ventilators

Fields of Study

  • Medicine

Readers

  • Cardiovascular Physiology
  • Oncology and Biomarker-Based Cancer Detection.