A Novel Vector Control Measure to Combat the Spread of Artemisinin Resistance in the Greater Mekong Subregion

Abstract

Survey for study site selection was conducted in 4 provinces, in Thailand; Ranong, Surat Thani, Ratchaburi and Kanchanaburi. Blood was collected by finger pricking from population at selected sites. Blood samples from people with malaria symptom were examined for malaria by RDT on site. Malaria examination by quantitative PCR or qMal was performed for all samples. More than 5,100 blood samples were collected, among this 346 of them had symptom during the survey. There were 35 samples positive for malaria by qMal and 4 samples were positive by RDT. Preliminary entomology surveys were conducted during reporting period for planning purpose for the vector survey which will be started in FY2018. Database management system has been established for the study including, but not limited to, blood survey forms, GIS mapping of sites, etc. Laboratory protocols have been validated and applied for blood survey and will be used for vector survey. Protocols for longitudinal blood survey and vector survey have been prepared and submitted for HRPO pre-review. Sites in Surat Thani will selected for the further longitudinal study based on recent analysis. Longitudinal surveillance will be conducted in FY2018 prior to ivermectin mass drug administration to ensure that there will be enough population with malaria for randomized controlled trial.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2017
Accession Number
AD1048440

Entities

People

  • Jetsumon Prachumsri
  • Kevin C Kobylinski
  • Wang Nguitragool

Organizations

  • Mahidol University

Tags

DTIC Thesaurus Topics

  • Age Groups
  • Body Temperature
  • Demography
  • Diseases And Disorders
  • Entomology
  • Health
  • History
  • Institutional Review Board
  • Malaria
  • Medical Personnel
  • Peroxides
  • Professional Development
  • Public Health
  • Site Selection
  • Social Sciences
  • Students
  • Thailand

Fields of Study

  • Medicine

Readers

  • Clinical Trial Research.
  • Parasitology and Pharmacology of Malaria.
  • Vector-Borne Disease and Entomology