Pathomechanics of Post-Traumatic OA Development in the Military Following Articular Fracture
Abstract
The objective of the proposed research is to develop new models for predicting the risk of post-traumatic osteoarthritis (PTOA) following intra-articular fracture (IAF). Aim 1, pursued this year, involved evaluating pre- and post-treatment CT data from patients with combat-related IAFs to measure fracture severity and post-reduction contact stress exposure. This study is being conducted in collaboration with the University of Iowa (PI: Donald Anderson, PhD) who is conducting these calculations on patients identified at the U.S. Army Institute of Surgical Research. IRB and HRPO approval has been obtained at both sites. Ongoing screening of potential subjects identified through the Department of Defense Trauma Registry has resulted in 64 fractures transferred and studied by the U of Iowa. Our partners at the U of Iowa continue to work on related efforts in civilian trauma patients to refine the measuring techniques. The military subjects pose some unique challenges in terms of injury severity but we remain confident that our collaborators skill in imaging analysis will remain successful as we study our military patients.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2017
- Accession Number
- AD1048792
Entities
People
- Jessica C. Rivera
Organizations
- Geneva Foundation