An in Vivo Investigation of Brain Inflammation in Gulf War Illness with Integrated PET/MR Imaging

Abstract

This project is aimed at evaluating the contribution of brain glia to the pathophysiology of Gulf War Illness, as well as fibromyalgia (a functional pain disorder characterized by similar symptoms). So far we have completed administrative and regulatory review, made substantial progress on subject enrollment, and completed some preliminary analyses. Over 400 participants have been pre-screened for the study. Of those, forty participants have completed the study, while an additional twenty-two participants were enrolled and found to be ineligible at the time of screening. Throughout the recruitment process, we have actively modified our inclusion criteria to address concerns of ambiguity as they have arisen. Recruitment was slower than anticipated initially, but has rapidly picked up over the past year and the study is now approaching completion.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2017
Accession Number
AD1049189

Entities

People

  • Marco L Loggia

Organizations

  • Massachusetts General Hospital

Tags

DTIC Thesaurus Topics

  • Anatomy
  • Biological Sciences
  • Biomedical Research
  • Body Weight
  • Brain
  • Central Nervous System
  • Cerebellum
  • Coding
  • Computer Programs
  • Department Of Defense
  • Diagnostic Imaging
  • Digital Data
  • Digital Information
  • Diseases And Disorders
  • Genotypes
  • Health Services
  • Hospitals
  • Identities
  • Inflammation
  • Information Operations
  • Magnetic Resonance
  • Magnetic Resonance Imaging
  • Maryland
  • Mathematics
  • Metadata
  • Nervous System
  • Notation
  • Operating Systems
  • Pain
  • Persian Gulf Syndrome
  • System Software
  • Thalamus

Readers

  • Clinical Trial Research.
  • Mathematics or Statistics
  • Neurotrauma and Rehabilitation Medicine.