Enhancing Immune Checkpoint Inhibitor Therapy in Kidney Cancer

Abstract

The purpose of this work is to develop strategies to enhance immune checkpoint inhibition in kidney cancer. The work is designed to test different strategies to induce or enhance the abscopal in a kidney cancer model by combining ablative techniques or TLR agonists with PD1 inhibitors. Funds were transferred to UT Southwestern mid 2017. The PI is in the process of getting IACUC/ACURO approval for the proposed animal studies.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2017
Accession Number
AD1049458

Entities

People

  • Hans-joerg Hammers

Organizations

  • University of Texas Southwestern Medical Center

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Biomedical Research
  • Department Of Defense
  • Electronic Mail
  • Immunotherapy
  • Information Operations
  • Inhibition
  • Inhibitors
  • Kidney Cancer
  • Maryland
  • Medical Personnel
  • Radiation
  • Students
  • Therapy
  • Universities

Readers

  • Immunology
  • Oncology (Cancer Research).