Non-Uniformly Sampled MR Correlated Spectroscopic Imaging in Breast Cancer and Nonlinear Reconstruction
Abstract
Magnetic Resonance Imaging (MRI) is an excellent anatomical tool to image tissue non-invasively. Dynamic contrast enhanced MRI (DCE-MRI) has excellent sensitivity but with varying specificity. MR Spectroscopy (MRS) enables biochemical characterization non-invasively of metabolites. Three major hypotheses are: (1) Accelerated 5-dimensional (5D)echo-planar imaging based correlated spectroscopic imaging (EP-COSI) acquisition produces multi-slice based multi-voxel two-dimensional (2D) MRS in a clinically feasible time. (2) Incorporating non-uniform under sampling (NUS) for spectral/spatial sampling into the 5D EP-COSI data acquisition and the group sparsity (GS)-based reconstruction will reduce the total acquisition time by at least a factor of 12.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2017
- Accession Number
- AD1051165
Entities
People
- Michael A Thomas
Organizations
- University of California