Assessing the Hemodynamic Effects of When Closed Chest Compressions are Augmented by Directing the Area of Maximal Compressions Over the Left Ventricle in a Swine Model of Pulseless Electrical Activity (Sus scrofa)
Abstract
To evaluate chest compressions over the left ventricle (LV) during PEA arrest. Methods: Transthoracic echocardiography was used to mark the aortic root (AR), and center of LV on 34 animals, which were randomized to receive chest compressions in one of the two locations. Hemorrhaged to MAP <20 to simulate traumatic PEA. 5 minutes post PEA, BLS was initiated for 10 minutes followed by ALS for 10 minutes. Hemodynamic variables were averaged over the final 2 minutes of BLS and ALS. Differences in rates of survival were analyzed using Fisher's exact test. A 2-way repeated measures analysis of variance was performed for the variables. Results: 6 of the LV group (35 ) achieved ROSC compared to 8 of the AR group (47 ). There was an in increase in aortic SBP (p=0.01), right atrial SBP (p<0.01) and right atrial DBP (p=0.02) at the end of BLS; no differences in hemodynamics during ALS. Conclusions: In our swine model of traumatic PEA, chest compressions performed directly over the LV improved blood pressures during BLS, but not ROSC.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 04, 2018
- Accession Number
- AD1051366
Entities
People
- Jacqueline R Evans
- Jeffrey Morgan
- Kenton Anderson
- Maria G. Castaneda
- Susan M. Boudreau
- Vikhyat S Bebarta
Organizations
- 59th Medical Wing