Determination of the Chronic Mammalian Toxicological Effects of RDX. Twenty-Four Month Chronic Toxicity/Carcinogenicity Study of Hexahydro-1,3,5-Trinitro-1,3,5-Triazine (RDX) in the B6C3F1 Hybrid Mouse. Phase 4, Volume 3, Appendix 11: Final Pathology Report

Abstract

In accordance with the amended experimental protocol gross and histopathologic examinations were performed on organs and tissues of B6C3F1 hybrid mice for IITRI Project L6121, Study Number 7. The mice were divided into five groups, each consisting of 85 males and 85 females. Four of the five groups were each treated with different doses of HEXAHYDRO-1,3,5-TRINITRO-1,3 and TRIAZINE (RDX) for twenty-four months. The mice of the fifth group did not receive RDX and did serve as a control group.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 1984
Accession Number
AD1053229

Entities

People

  • Barry S. Levine
  • E. M. Furedi
  • John M. Sagartz
  • Paul M. Lish
  • Vladislava S. Rac

Organizations

  • IIT Research Institute

Tags

Communities of Interest

  • Counter IED

DTIC Thesaurus Topics

  • Animals
  • Bone Marrow
  • Capillary Electrophoresis
  • Carbon Dioxide
  • Cecum
  • Cells
  • Epithelium
  • Experimental Design
  • Glands
  • Histopathology
  • Laboratory Animals
  • Lymph Nodes
  • Lymphatic System
  • Mammary Glands
  • Medical Personnel
  • Neoplasms
  • New York
  • Nodes
  • Observation
  • Pathology
  • Quality Assurance
  • Sarcoma
  • Spinal Cord
  • Terminals
  • Test And Evaluation
  • Therapy
  • Three Dimensional
  • Tissues
  • Triazines
  • Urinary Tract

Readers

  • Agricultural Chemistry/Soil Science
  • Immunology
  • Technical Research and Report Writing.