In-Home Sleep Recordings in Military Veterans With Posttraumatic Stress Disorder Reveal Less REM and Deep Sleep <1 Hz

Abstract

This study shows altered sleep patterns in sleepers with PTSD that can be partially accounted for by age and medication use; however, differences in deep sleep related to PTSD could not be linked to any known factor. With several medications [prazosin, selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs); p < 0.03], as well as SSRIs were associated with less sleep efficiency (b = -3.3 0.95; p = 0.0005) and more sleep fragmentation (b = -1.7 0.51; p = 0.0009). Anti-psychotics were associated with less sleep efficiency (b = -4.9 1.4; p = 0.0004). Sleep efficiency was negatively impacted by SSRIs, antipsychotic medications, and depression (p < 0.008). Increased sleep fragmentation was associated with SSRIs, SNRIs, and anxiety (p < 0.009), while prazosin and antipsychotic medications correlated with decreased sleep fragmentation (p < 0.05).

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Document Details

Document Type
Technical Report
Publication Date
May 11, 2018
Accession Number
AD1054157

Entities

People

  • Dae Y. Kang
  • Julie Onton
  • Scott C. Matthews
  • Todd P Coleman

Organizations

  • Naval Health Research Center

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Algorithms
  • Anticonvulsants
  • Antidepressants
  • Anxiety Disorders
  • Brain
  • Department Of Defense
  • Department Of Veterans Affairs
  • Drug Abuse
  • Drug Addiction
  • Governments
  • Hypnotics And Sedatives
  • Nervous System
  • Psychiatry
  • Tranquilizing Agents
  • Traumatic Stress Disorder
  • United States
  • United States Government

Fields of Study

  • Medicine
  • Psychology

Readers

  • Cardiovascular Physiology
  • Circadian Sleep-Wake Regulation and Chronobiology
  • Mental Health of Military Veterans with Posttraumatic Stress Disorder (PTSD): Risk Factors, Prevalence, Symptoms, and Treatment.