Assessment of Paper Types for Cell Free Reactions

Abstract

Cell-free systems are currently targeted as a potential method to enhance the detection of chemical and biological threats in the environment. Recent studies have shown a functional way to carry out cell-free reactions on paper. Freeze-drying cell-free reaction solutions onto paper can provide convenient field-forward characteristics such as low weight, easier handling and distribution, and long-term storage capabilities. The work described herein focuses on the exploration and testing of several materials that can be used for cell-free reactions. A variety of chromatography papers and synthetic filter membranes were examined to identify suitable materials for qualities such as portability, stability, flexibility, in-field viability, relatively low cost, and favorable surface properties that allow for quick display and optimum brightness of colorimetric output.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2018
Accession Number
AD1057327

Entities

People

  • Glory Mgboji
  • Matthew P Lux
  • Steven Blum
  • Vanessa Funk

Organizations

  • Oak Ridge Institute for Science and Education

Tags

Communities of Interest

  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Albumins
  • Biological Sciences
  • Cell-Free System
  • Chemical Reactions
  • Chemistry
  • Chromatography
  • Deoxyribonucleic Acids
  • Department Of Defense
  • Detection
  • Drying
  • Environment
  • Filter Paper
  • Freeze Drying
  • Materials
  • Materials Testing
  • Military Research
  • Nucleic Acids

Readers

  • Analytical Chemistry
  • Computational Modeling and Simulation