Modeling Subconscious Vision

Abstract

This grant supported work exploring subconscious vision through mathematical modeling. Mathematical modeling has had a tremendous impact on our understanding of conscious vision. Recently, a separate subconscious visual system was discovered in the retina, mediated by intrinsically photosensitive retinal ganglion cells (ipRGCs) which can function in the absence of rods and cones. We used mathematics to classify the responses of ipRGCs and developed mathematical models of their electrical activity. We then developed numerical methods that allowed for a large scale simulation of the entire retina. Studying a target of ipRGCs, the suprachiasmatic nucleus (SCN), which forms the central daily (circadian) clock in the brain, we showed that the SCN processes subconscious visual information to enhance visual function. Further studying the effects of light on circadian timekeeping, we developed a smartphone app, Entrain, to help adjust human circadian rhythms. This app was installed nearly 200,000 times. Data collected from the app resulted in one of the largest studies of human sleep.

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Document Details

Document Type
Technical Report
Publication Date
Feb 28, 2017
Accession Number
AD1058669

Entities

People

  • Daniel B. Forger

Organizations

  • University of Michigan

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Abstracts
  • Agreements
  • Biological Rhythms
  • Brain
  • Circadian Rhythms
  • Computational Neuroscience
  • Department Of Defense
  • Differential Equations
  • Engineering
  • Experimental Data
  • Mathematical Models
  • Mathematics
  • Neurosciences
  • Partial Differential Equations
  • Simulations
  • Standards
  • Students

Readers

  • Agent-Based Social Robotics and Mobile-Assisted Learning in Virtual Environments.
  • Circadian Sleep-Wake Regulation and Chronobiology
  • Vision Science/Vision Psychology/Cognitive Neuroscience.