Morphological and Mechanical Characterization of Adolescent Yucatan Miniature Porcine Skull

Abstract

Traumatic brain injury is the signature injury endured during the military conflicts in Iraq and Afghanistan resulting from blast and blunt/ballistic impact. Computational simulation based on realistic material models can be utilized to better understand the biomechanics of traumatic brain injury. To develop accurate material models, the material response of biological constituents, such as tissue and bone, must be understood. In addition, an in-depth evaluation of the micro-structural components of the skull and their response to mechanical loading may aid in understanding the mechanisms of injury. The current study examines the mechanical response and structural properties of the Yucatan minipig cranial bone (skull) to help develop material models inspired by its structure. This species is useful to study traumatic head injury because its gyroencephalic brain (hemispheres with convolutions) is more similar to the human brain than small animal models (i.e., rodents). However, this animal skull is uniform, which differentiates it from the human three-layer sandwich skull structure.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2018
Accession Number
AD1060424

Entities

People

  • C. A. Gunnarsson
  • Stephen L. Alexander
  • Tusit Weerasooriya

Organizations

  • United States Army Research Laboratory

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Adolescents
  • Apparent Density
  • Brain Injuries
  • Cameras
  • Compressive Strength
  • Department Of Defense
  • Elastic Properties
  • Engineering
  • Fungi
  • Head Injuries
  • Ionizing Radiation
  • Liquid Chromatography
  • Materials
  • Measurement
  • Mechanical Engineering
  • Mechanical Properties
  • Mechanical Working
  • Mechanics
  • Military Research
  • Modulus Of Elasticity
  • Orientation (Direction)
  • Simulations
  • Skull
  • Stresses
  • Structural Components
  • Two Dimensional
  • X Rays

Readers

  • Computational Modeling and Simulation
  • Neurotrauma and Rehabilitation Medicine.
  • Structural Dynamics.