In Vivo Detection of Gaseous Microemboli during AE using Cardiohelp ECLS

Abstract

This is the first report of GME detection in a modern ECLS device during aeromedical evacuation of subjects with ARDS at ground and various altitudes. Ascent to 8 and more so to 30K led to sustained elevation of GME levels in all ranges vs. ground level. There was no significant difference in GME counts between uninjured and injured states. GME 100um were not significantly increased possibly due to the presence of the ML.ML may trap larger GME and prevent them from re-entering the animals systemic circulation. GME may be an important contributor to end organ damage during transport of subjects at altitudes above 8K feet.

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Document Details

Document Type
Technical Report
Publication Date
Aug 20, 2018
Accession Number
AD1061517

Entities

People

  • Andriy I. Batchinsky
  • Brendan M Beely
  • George T. Harea
  • Jae-hyek Choi
  • Teryn R. Roberts
  • Valerie G. Sams
  • Vitali Karaliou

Organizations

  • 59th Medical Wing

Tags

DTIC Thesaurus Topics

  • Aeromedical Evacuation
  • Air Force
  • Altitude
  • Boyle'S Law
  • Cardiovascular System
  • Catheterization
  • Decompression Sickness
  • Detection
  • Detectors
  • End Organs
  • Evacuation
  • Gas Embolism
  • Ground Level
  • Health Services
  • Military Medicine
  • Veins
  • Wounds And Injuries

Readers

  • Aquatic Ecology
  • Trauma Surgery or Emergency Medicine.
  • Trauma or Military Medicine