Colorimetric Biosensor: Porphyrin Variations

Abstract

This report is related to an effort that seeks to develop autonomous sensors for environmental monitoring of changes in bacterial populations. The approach uses porphyrin modified antimicrobial peptides to produce colorimetric signatures, enabling the use of devices originally developed for chemical sensing applications. Here, we describe initial work focused on development of the covalent porphyrin-peptide constructs and the evaluation of those materials in the presence and absence of bacterial targets in aqueous solution

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Document Details

Document Type
Technical Report
Publication Date
Oct 03, 2018
Accession Number
AD1061568

Entities

People

  • Apre Gleaves
  • Brandy J. Johnson
  • Chris R. Taitt
  • Edikan Archibong
  • Iwona A. Leska
  • Stormie Monk

Organizations

  • United States Naval Research Laboratory

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Amino Acids
  • Anti-Infective Agents
  • Aqueous Solutions
  • Bacteria
  • Biosensors
  • Chemical Synthesis
  • Chemistry
  • Coordination Complexes
  • Data Analysis
  • Data Sets
  • Detection
  • Detectors
  • Engineering
  • Materials
  • Military Research
  • Organic Chemistry
  • Target Recognition

Readers

  • Molecular and Cellular Biochemistry
  • Sensor Fusion and Tracking Systems.

Technology Areas

  • Biotechnology