Microglial-Derived Microparticles Mediate Neuroinflammation after Traumatic Brain Injury

Abstract

Local and systemic inflammatory responses are initiated early after traumatic brain injury (TBI), and may play a key role in the secondary injury processes resulting in neuronal loss and neurological deficits. However, the mechanisms responsible for the rapid expansion of neuroinflammation and its long-term progression have yet to be elucidated.

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Document Details

Document Type
Technical Report
Publication Date
Mar 15, 2017
Accession Number
AD1061806

Entities

People

  • Alan I. Fade
  • Alok Kumar
  • Asit Kumar
  • Bogdan A. Stoica
  • David J. Loane
  • Gelareh Abulwerdi
  • Ming Yang
  • Niaz Khan
  • Stephen R. Thom

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Blood
  • Brain Injuries
  • Cell Membrane
  • Cell Physiological Processes
  • Cells
  • Cellular Structures
  • Culture Media
  • Culture Techniques
  • Diseases And Disorders
  • Gene Expression
  • Inflammation
  • Microparticles
  • Molecules
  • Myeloid Cells
  • Neurodegeneration
  • Neuroglia
  • Surgery

Fields of Study

  • Medicine

Readers

  • Immunology
  • Molecular Biology and Genetics
  • Traumatic Brain Injury (TBI) and Cognitive Aging in the Guam and Border Populations Affected by Alzheimer's Disease and Tau-Associated Dementias.