New Therapies for Fibrofatty Infiltration

Abstract

The goal of this project is to test three classes of compounds in animal models of muscular dystrophy, and evaluate their therapeutic potential in preventing fibrofatty infiltration. Animals and drugs required for the project have been procured. A change has been made to the kinase inhibitor compound to be tested in animal models of disease, as a more efficacious drug was identified with similar substrate specificity.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2018
Accession Number
AD1063934

Entities

People

  • Fabio M Rossi

Organizations

  • University of British Columbia

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • British Columbia
  • Department Of Defense
  • Fibrosis
  • Information Operations
  • Inhibitors
  • New Hampshire
  • Patent Applications
  • Professional Development
  • Side Effects
  • Standards
  • Students
  • Substrate Specificity
  • Substrates
  • Technology Transfer
  • Therapy
  • United States

Fields of Study

  • Biology

Readers

  • Immunology and Pathology
  • Oncology