Analysis of Stable Isotopes by Triple Quadrupole GC/MS (GC-QQQ) for the Determination of Metabolic Flux and Stress Resistance (Resiliency)

Abstract

The instrument proposal was for acquisition of a Triple Quadrupole GC/MS (GC-QQQ) to markedly increase throughput, method development, and current stable isotope analysis capabilities. Using the GC-QQQ purchased, we have made progress in establishing sensitive approaches to assessing both metabolism and stress resistance using a variety of models (in vitro, animal, and human subjects) to address our hypotheses. The expanded instrumentation in our laboratory has led to new collaborations, new proposal submissions including 2 in review at ARO, 6 new publications, and many more in preparation/review. We now provide expanded student research training including those via HSAP/URAP mechanisms.

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Document Details

Document Type
Technical Report
Publication Date
Jan 19, 2017
Accession Number
AD1064331

Entities

People

  • Benjamin F. Miller
  • Karyn L. Hamilton

Organizations

  • Colorado State University

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Acquisition
  • Agreements
  • Contractors
  • Department Of Defense
  • Education
  • Engineering
  • Information Operations
  • Instrumentation
  • Mathematics
  • Metabolism
  • Military Research
  • Resistance
  • Standards
  • Students
  • Technology Transfer

Readers

  • Prostate Cancer Biology.
  • Quantum spin resonance or Electron Paramagnetic Resonance spectroscopy.
  • Research Science/Academic Research