Discover Novel Therapeutic Strategies for Peritoneal Metastases from Gastric Adenocarcinoma

Abstract

The major goals of the project during the reporting period were to (1) optimize purification of tumor cells and exosomes from gastric adenocarcinoma ascites, and (2) to initiate proteomic profiling of these disseminated GAC cells and exosomes. We completed untargeted MS proteomic profiling of a total of 10 (52.5 of SOW) gastric cancer ascites derived cell specimens. We commenced proteomic profiling of exosomes derived from gastric cancer cell lines.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2018
Accession Number
AD1064687

Entities

People

  • Hanash M. Samir

Organizations

  • University of Texas at Austin

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Adenocarcinoma
  • Biomedical Research
  • Cancer
  • Carcinoma
  • Cell Line
  • Cells
  • Communities
  • Culture Media
  • Department Of Defense
  • Electron Microscopy
  • Governments
  • Information Operations
  • Institutional Review Board
  • Instructors
  • Law
  • Local Governments
  • Maryland
  • Medical Personnel
  • Neoplasms
  • Patent Applications
  • Proteins
  • Proteomics
  • Stem Cells
  • Targets
  • Technology Transfer
  • Therapy
  • Training
  • Universities

Fields of Study

  • Biology

Readers

  • Forest Ecology
  • Oncology (Cancer Research).
  • Oncology and Biomarker-Based Cancer Detection.

Technology Areas

  • Biotechnology