Distributed Spatiotemporal Dynamics of Synthetic Gene Circuits
Abstract
In this project we developed a multi-scale computational approach for analysis of multi-cellular processes in large bacterial populations and design of distributed synthetic gene circuits. This approach integrates discrete agent simulations of single cells with PDE modeling of large-scale dynamics. We applied this framework to computational modeling of spatiotemporal dynamics of growing bacterial biofilms and the dynamics of multi-strain bacterial populations.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 12, 2018
- Accession Number
- AD1064759
Entities
People
- Lev S Tsimring
Organizations
- University of California