Targeting BRCAness in Gastric Cancer

Abstract

In the past year, we have made substantial progress in the projects goals. We have set up a system (described below) to interrogate gastric cancer cells with ATR and PARP inhibitors. This screening platform is now up and running and we are prosecuting preliminary hits. Over the next year, we will validate hits generated here and further the interrogation of clinical samples.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2018
Accession Number
AD1064860

Entities

People

  • Lawrence Fong

Organizations

  • University of California Regents

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • California
  • Cancer
  • Cell Count
  • Cell Line
  • Cell Physiological Processes
  • Cells
  • Chemotherapy
  • Clinical Trials
  • Department Of Defense
  • Diseases And Disorders
  • Genes
  • Genomic Instability
  • Inhibition
  • Inhibitors
  • Law
  • Materials
  • Mutations
  • Neoplasms
  • Patent Applications
  • Platinum
  • Prostate Cancer
  • Targeting
  • Therapy

Fields of Study

  • Biology

Readers

  • Forest Ecology
  • Oncology