Central Visual Prosthesis with Interface at the Lateral Geniculate Nucleus

Abstract

The goals of this project are to: Modify microfabrication methods to produce 256 channel, implantable electrode arrays for the Lateral Geniculate Nucleus (LGN); Adapt visual neuroprosthesis RF coil and titanium package to fit in small hole in skull; update external controller software; Develop surgical insertion tool to deliver the electrodes to LGN; In vitro bench testing of electrode arrays and insertion tools; In vivo implantation and psychophysical testing in non-human primate animal model.The main accomplishments under this award were a) the development of viable, microfabricated deep-brain stimulation electrodes and the means to deploy them using a unique, custom surgical insertion tool; this assembly was the subject of a provisional patent application filed by sub-awardee Bionic Eye Technologies, Inc. and b) the development of very low-stress Silicon Nitride material for the substrate on which the penetrating electrodes were micro-fabricated. This material was tested extensively in agarose gel models of brain tissue.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2018
Accession Number
AD1064869

Entities

People

  • Joseph F. Rizzo

Organizations

  • Massachusetts Eye and Ear Infirmary

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Assembly
  • Ceramic Materials
  • Electric Stimulation Therapy
  • Electrodes
  • Fabrication
  • Health Services
  • Implantation
  • Manufacturing
  • Materials
  • Medical Personnel
  • Microfabrication
  • Patent Applications
  • Patents
  • Prostheses And Implants
  • Silicon Carbide
  • Substrates

Readers

  • Integrated Circuit Design and Technology.
  • Neuroscience
  • Vision Science/Vision Psychology/Cognitive Neuroscience.

Technology Areas

  • Biotechnology