In Vitro Dermal Corrosion Proficiency Demonstration, April 2018-September 2018

Abstract

Prior to routine use of any of the four validated in vitro dermal corrosion test methods specified in the OECD guideline, technical proficiency must be demonstrated using the twelve Proficiency Substances listed in the OECD guideline. This study was conducted as a proficiency demonstration. Proficiency substances were tested using the EPI-SCT-200 assay. All assay acceptance criteria were met and 100 of the proficiency substances were correctly classified, therefore the performing lab is technically proficient and EPI-SCT-200 may be routinely used for in vitro prediction of skin corrosion.

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Document Details

Document Type
Technical Report
Publication Date
Feb 08, 2019
Accession Number
AD1067472

Entities

People

  • Emily M. Lent

Organizations

  • United States Army Center for Health Promotion and Preventive Medicine

Tags

DTIC Thesaurus Topics

  • Acetic Acid
  • Acids
  • Benzaldehydes
  • Classification
  • Corrosion
  • Demonstrations
  • Ethanolamine
  • Fatty Acids
  • Glyoxylic Acid
  • Health
  • Hydrochloric Acid
  • Inorganic Acids
  • Instructions
  • Lactic Acid
  • Materials
  • Organic Acids
  • Personnel Management
  • Public Health
  • Quality Assurance
  • Quality Control
  • Spreadsheet Software
  • Test And Evaluation
  • Test Methods
  • Therapy
  • Tissues
  • Toxicity
  • Toxicology
  • Validation
  • Viability

Fields of Study

  • Medicine

Readers

  • Instructional Design and Training Evaluation.
  • Toxicology/Environmental Toxicology