Development of Human Mesenchymal Stem Cells for Treatment of Multiple Disorders

Abstract

Stem cells are those that can differentiate into other functionally varied cell types, such as nerve, muscle, bone, and skin cells. Stem cells represent various temporal and spatial stages in organismal development, and therefore their capacity to differentiate into other cells is variable. Embryonic stem cells are those that are isolated from a very early embryonic development, the blastocyst stage. Such cells retain the capacity to form all tissue types of an organism. Adult stem cells are those isolated from different tissues once such tissues have definitively formed, including any adult stage. Such cells have different capacities to differentiate into other cell types, but no capacity to form all tissue types that make an organism. A common type of adult stem cells is the mesenchymal stem cells (MSCs), typically isolated from bone marrow, adipose tissue, and umbilical cord blood.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2018
Accession Number
AD1068837

Entities

People

  • Ghulam J. Chaudry
  • Hui Xia
  • Jamie L. Myers
  • Manuel Caballero

Organizations

  • 59th Medical Wing

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Adipose Tissue
  • Air Force
  • Antigens
  • Bone Marrow
  • Cells
  • Connective Tissue Cells
  • Diseases And Disorders
  • Fat Cells
  • Fluorescence
  • Gene Expression
  • Growth Factors
  • Materials
  • Osteoblasts
  • Peptide Growth Factors
  • Proteins
  • Stem Cells
  • Stromal Cells

Fields of Study

  • Biology

Readers

  • Immunology and Pathology
  • Molecular and Cellular Biology

Technology Areas

  • Biotechnology