Rapid Preconcentration and Detection of Pathogens in Large Volumes via Dual-Nanoparticle Targeting
Abstract
The PI has had good success in this basic research project. In summary, the PI has demonstrated that the zwitterionic buffers are anideal medium of choice for dielectric response measurements of colloidal suspensions irrespective of the particle type. HEPES inparticular behaves like an anion at pH 8.5 but its unique molecular structure lends it a special status that cannot be explained by thecurrent analytical models; the lower detection limit of 0.0025% w/v obtained in both Au NP and PS suspensions is unprecedented inthe literature. Also, the long range particle-particle interactions become important at dilutions as low as 0.005 w/v % to 0.007 w/v %.There are 2 papers under preparation or under review as a direct result of this AOARD grant.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 08, 2019
- Accession Number
- AD1076500
Entities
People
- Shalini Gupta
Organizations
- Indian Institute of Technology Delhi