Moxifloxacin-Induced Sweet Syndrome in a 85-year-old Female with Prosthetic Joint Infection

Abstract

An 85-year old female with history of recurrent Streptococcus Agalactiae bacteremia with cardiovascular implantable electronic device lead vegetations and bilateral hip arthroplasties presented to the Emergency Department with concern for right hip cellulitis. Culture of joint aspirate was performed and grew Strep Agalactiae. The patient declined orthopedic surgical intervention and was started on intravenous antibiotics then transitioned to daily moxifloxacin 400mg by mouth. After several weeks of moxifloxacin therapy, the patient developed low grade fevers, malaise, and painful cutaneous lesions on both hands (Figure 1 and 2). Laboratory evaluation was significant for an elevated ESR (86mm/hr), CRP(22mg/dL) and a normal WBC count. She was referred to dermatology for evaluation and a biopsy of a representative lesion was performed with a clinical differential diagnosis of Sweet syndrome, Janeway lesions, and erythema muliforme.

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Document Details

Document Type
Technical Report
Publication Date
Apr 25, 2019
Accession Number
AD1081752

Entities

People

  • Brittany Lenz
  • Jacob G. Dodd
  • Jared Roberts
  • Justin Bandino

Organizations

  • 59th Medical Wing

Tags

Fields of Study

  • Medicine

Readers

  • Immunology
  • Toxicology/Environmental Toxicology
  • Trauma Surgery or Emergency Medicine.

Technology Areas

  • Microelectronics