Microwave Ablation of Eccrine Glands as a Treatment for Residual Limb Hyperhidrosis

Abstract

Up to 66 percent of lower limb amputees report residual limb hyperhidrosis with a significant association between sweating and decreased prosthetic function. Microwave thermoablation is an effective permanent solution for axillary hyperhidrosis. The purpose of this study was to evaluate the use of microwave thermoablation for the treatment of residual limb hyperhidrosis. Dermatology Life Quality Index (DLQI) scores, Severity of Prosthesis Problem Scale (SPPS) scores, and gravimetric measurements of sweat after 10 minutes of exercise were taken at baseline and 3 months after treatment. Pre and post treatment measurements were compared using the Wilcoxon signed-rank test using SPSS (IBM, Armonk, NY). A total of 9 limbs in 8 patients (one double amputee) underwent treatment. There was a statistically significant decrease in DLQI (Z=-2.136, p=0.033) and SPPS (Z=-2.521, p=0.012) scores indicating improvement in quality of life and increased ease of prosthetic use, respectively. There was a statistically significant decrease in gravimetric amount of sweat produced (Z=-2.032, p=0.042). Microwave thermoablation significantly improves quality of life, increases ease of prosthetic use, and decreases amount of sweat produced in lower limb amputees. These effects are expected to be permanent.

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Document Details

Document Type
Technical Report
Publication Date
Sep 17, 2019
Accession Number
AD1082322

Entities

People

  • Timothy A. Durso

Organizations

  • 59th Medical Wing

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Ablation
  • Amputees
  • Anesthesia
  • Contracts
  • Government Procurement
  • Governments
  • Lower Limb Amputees
  • Measurement
  • Prostheses And Implants
  • Prosthetics
  • Quality Of Life
  • Residual Limbs
  • Risk
  • Risk Analysis
  • Sweat Glands
  • Task Forces
  • Therapy

Fields of Study

  • Medicine

Readers

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  • Regression Analysis.
  • Trauma Surgery or Emergency Medicine.